Americans, we get it, you have no healthcare system worth the name. Stop assuming nobody else worldwide can get the meds either.
Exactly. Functional public health systems will assess patient outcomes and the expenditure in money and resources to determine what treatments get approved.
The odds are pretty good that - if this works out - this will be on the list of approved treatments straight away. Surgery is an expensive and high-load pathway for public health systems. A non-surgical treatment that gives good outcomes is such a win-win for both patients and public health systems that it almost doesn’t matter how much it costs.
When they compared cartilage from young and old mice, they found that levels of 15-PGDH approximately doubled with age. To test the idea, researchers treated older mice with a small molecule drug that blocks 15-PGDH activity. [And cartilage regrew.]
Sounds very promising! I couldn’t figure out the peer-reviewed-ness status.
Ready for someone to tell me why this unfortunately won’t work / become mainstream
Well, this same drug (working name MF-300) is a PDGH-15 inhibitor and has already been through phase 1 human trials for a separate condition.
Because PDGH-15 also causes age related muscle weakness.
Now, PDGH-15 also plays a role in cancer prevention, and there may be a few other less obvious functions.
I don’t know if the results of the phase 1 trials have been published yet, but it’s been a while since I checked.
I’ve been hearing about MF-300 for a little under a year, and with these same claims about restoring cartilage.
Money, usually. Or cancer. God i sound depressing 😄
Money cancer.
Ah, the billionaires again.
This and then the new about regrowing teeth. Its a very exciting time in medicine.
If you think anyone but the elite will be able to afford or procure these procedures, you’re incredibly optimistic.
As soon as it gets approved, some shitty corporation will purchase the patent and lock it behind a paywall for 80+ year old geriatrics with zero fucks given towards people who actually deserve or need it.
This drug can be delivered via pill. It has a range of effects in reversing age related damage.
I’m not sure if it will be kept to the rich, or given out widely to justify the removal of social security, or at least jacking up the retirement age.
If the worker-slaves live longer, you don’t have to indoctrinate & capture new ones quite as often!
I’d like my partners knees to work again so they can do the things they like as they age, like riding bikes or hiking.
So… anywhere but the USA it will be affordable(ie free) anyways? Okay.
Bremonia will have the procedures, for free. The name can be changed, I don’t care. I just need help overthrowing a few corrupt governments and I’m out.
Lol Yankee problems
I’m not a Yankee, but thanks for assuming
You’re an American, that’s what Yankee means to everybody outside the states.
I’m old school American
#landback!!!
Finally some good fucking news.
I’m in this thumbnail and I want that right now.
Just in time for me to get old!
Wrong end of the stick, as usual
Amazing!
